Paratensile signaling
http://www.larc.tsinghua.edu.cn/post/1064 WebParatensile signaling enables instantaneous and long-range mechanotransduction via collagen fibers (less than 1 s over 70 μm) to activate a single fibroblast, which is …
Paratensile signaling
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WebProceedings of the National Academy of Sciences of the United States of ... WebFig. 2. Single-cell-level intercellular paratensile signaling in vitro. (A) Collagen matrix deformation induced by a single fibroblast before and after TGF-β activation measured …
WebThe instantaneous long-range transmission of mechanical cues between cells through collagen fibers is regulated by paratensile signaling, which is a recently reported mechanical communication mode separate from paracrine signaling that interprets … WebMay 1, 2024 · Paratensile signaling enables instantaneous and long-range mechanotransduction via collagen fibers (less than 1 s over 70 μm) to activate a single …
WebMatrix-transmitted paratensile signaling enables myofibroblast-fibroblast cross talk in fibrosis expansion 3 years ago By Longwei Liu , Hongsheng Yu , Hui Zhao , Zhaozhao … WebFig. 1. Schematic illustration defining the hypothesis of paratensile signaling in fibrosis expansion. Conceptual illustration of single-cell-level intercellular paratensile signaling in fibrosis expansion, which mainly involves three stages, including 1) force generation by a myofibroblast, 2) force transmission through the fibrous matrix, and 3) …
WebAug 26, 2024 · The requirement of integrin signalling supports the key role of mechanic tissue properties in fibrogenesis. Paratensile signalling between fibroblasts 7 or location-dependent TGFβ mechano-signalling in pulmonary fibrosis progression 8 also evidence the role of mechano-transduction in fibrosis.
WebJan 1, 2024 · Recent advances highlight the evolvement of intracellular mechanotransduction pathways responding to ECM remodeling and abnormal hemodynamics (i.e., low and disturbed shear stress, pathological stretch, and increased pressure), which are prevalent biomechanical characteristics of fibrosis in multiple organs … mama choice asi boosterWebmechanocommunications are also known as paratensile sig-naling.24 They involve the transmission between fibroblasts of instantaneous and long- range mechanical signals that are created by the cells tugging on the aligned fibers in which they are interspersed.24,26-28 This signaling activates the fi- mama chinedu net worthWebvia the fibrous matrix, which we termed paratensile signaling. Para-tensile signaling enables instantaneous and long-range mechano-transduction via collagen fibers (less … mama chow\u0027s kitchen menuWebAug 26, 2024 · Paratensile signalling between fibroblasts 7 or location-dependent TGFβ mechano-signalling in pulmonary fibrosis progression 8 also evidence the role of … mamaclean crowdfundingWebJan 1, 2024 · (A) Proper matrix mechanical properties, hemodynamics, and paratensile signaling regulate homeostasis in inflammation, endothelial, and epithelial maintenance, … mama chicken agraWebThis study fills a gap in the literature by conducting a systematic comparison of cartilage and chondrocyte characteristics from these two zones. It also investigates whether cho... View... mama chola translationWebMay 1, 2024 · Paratensile signaling enables instantaneous and long-range mechanotransduction via collagen fibers (less than 1 s over 70 μm) to activate a single fibroblast, which is intracellularly mediated by DDR2 and integrin signaling pathways in a calcium-dependent manner through the mechanosensitive Piezo1 ion channel. mama chinedu is dead