Mouse cathepsin b protein
NettetThe mouse cathepsin B gene and its flanking regions were cloned and characterized. The gene contains 10 exons and 9 introns spanning about 20 kb. Although the exon … NettetHigh levels of cathepsin B are found in macrophages and osteoclasts, as well as various types of cancer cells, including lung, colon, prostate, breast, and stomach. In addition, expression of cathepsin B has been associated with multiple sclerosis (3), rheumatoid arthritis (4), and pancreatitis (5). While generally localized to lysosomes, in ...
Mouse cathepsin b protein
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NettetSimilar Proteins; P28293 · CATG_MOUSE. Protein. Cathepsin G. Gene. Ctsg. Status. UniProtKB reviewed (Swiss-Prot) Organism. Mus musculus (Mouse) ... Cleaves the synovial mucin-type protein PRG4/lubricin. Cleaves and activates IL36G which promotes expression of chemokines CXCL1 and CXLC8 in keratinocytes. Nettet8. apr. 2024 · Hook VY, Kindy M, Reinheckel T, Peters C, Hook G. Genetic cathepsin B deficiency reduces beta-amyloid in transgenic mice expressing human wild-type …
Nettet25. jul. 2014 · The results of this study show that BACE1 and cathepsin B protein levels are higher in the hippocampus of 9-month-old SAMP8 mice than those of age-matched SAMR1 mice. Administration of sildenafil significantly reduced the synthesis of both β-secretase enzymes probably through the modulation of calpain/Cdk5/p25 and p … NettetHSP40 Proteins Use Class-Specific Regulation to Drive HSP70 Functional Diversity; IL-33-PU.1 Transcriptome Reprogramming Drives Functional State Transition; ... Mouse Cathepsin B ELISA Kit [Colorimetric] (CAT#: NPP2011ZP395) Cathepsin B Activity Fluorometric Assay Kit, Mammalian (CAT#: NK1120FY061)
Nettetprotein coding gene: Chr14:63359911-63383372 (+) 129S1/SvImJ: ... CTSB, cathepsin B Vertebrate Orthologs 4 Vertebrate Orthology ... et al., Nucleotide and predicted amino acid sequences of cloned human and mouse preprocathepsin B cDNAs. Proc Natl Acad Sci U S A. 1986 Oct;83(20):7721-5. NettetAnti-mouse Cathepsin B antibody Microplate (12 x 8 wells) 1 unit. Avidin-Biotin-Peroxidase Complex (ABC) 1 x 130µl. Biotinylated anti-mouse Cathepsin B antibody 1 x 130µl. Lyophilized recombinant mouse Cathepsin B standard 2 x 10ng. Plate Seal 1 x 4 units. Sample Diluent Buffer Green Cap 1 x 30ml. TMB Color Developing Agent Amber …
Nettet7. des. 2024 · cathepsin B Antibody (H-5) is an IgG 2b κ mouse monoclonal cathepsin B antibody (also designated CTSB antibody) suitable for the detection of the cathepsin B …
Nettet21. jun. 2005 · Cathepsin B. Gene. CTSB. Status. UniProtKB reviewed (Swiss-Prot) Organism. Homo sapiens (Human) Amino acids. 339. Protein existence. Evidence at protein level. ... Thiol protease which is believed to participate in intracellular degradation and turnover of proteins (PubMed:12220505). Cleaves matrix extracellular … rspsi map editor with valius pluginNettetRecombinant Mouse Cathepsin B Protein (Met1-Phe339) 50084-M08H with a fusion His Tag, is expressed in HEK293 Cells. With high purity, high biological activity, high … rspsi map editor downloadNettetCathepsin B (CTSB) is a lysosomal protease, and several human cancers are reported highly expressing CTSB. Many optical methods have been developed for CTSB detection but not a bioluminescence (BL) probe. Herein, a CTSB-specific bioluminescence probe Val-Cit-AL was rationally designed for selectively sensing CTSB activity in vitro with a … rspt family fitnessNettetMaterials. Recombinant Mouse Cathepsin L (rmCathepsin L) (Catalog # 1515-CY) Activate rmCathepsin L at 100 µg/mL in Activation Buffer. Incubate at room … rspt torontoCathepsin B has been proposed as a potentially effective biomarker for a variety of cancers. Overexpression of cathepsin B is correlated with invasive and metastatic cancers. Cathepsin B is produced in muscle tissue during metabolism. It is capable of crossing the blood–brain barrier and is associated with neurogenesis, specifically in the mouse dentate gyrus. A wide array of diseases result in elevated levels of cathepsin B, which causes numerous pathological processes including cell … rsps with tobNettet12. feb. 2024 · Also known as. CB. Summary. This gene encodes a member of the peptidase C1 family and preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to generate the double chain form of the enzyme. rspxkgyfyy 126.comNettetI dag · Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. © 2024 Published by Elsevier B.V. 1 Combined exposure to benzo(a)pyrene and dibutyl phthalate aggravates pro-inflammatory macrophage polarization in spleen via pyroptosis … rsptechnology