Blc chemokine
WebFeb 19, 1998 · BLC strongly attracts B lymphocytes while promoting migration of only small numbers of T cells and macrophages, and therefore is the first chemokine to be … WebRecently, a CXCR5 ligand, termed B lymphocyte chemoattractant (BLC) or B cell attracting chemokine (BCA)-1 (15, 16), has been found constitutively expressed by stromal cells in lymphoid follicles and has been proposed to act as a B cell homing chemokine .
Blc chemokine
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WebAug 7, 2001 · The CXC chemokine CXCL13, known as BCA-1 (B cell-attracting chemokine 1) or BLC (B-lymphocyte chemoattractant), has been identified as an efficacious … WebChemokines belong to the largest subgroup of cytokines, with approximately 45 present in humans. Chemokine genes are found in vertebrates from teleost fish to humans. Chemokines are classified according to the number and arrangement of conserved cysteine residues. All but two chemokines contain four conserved cysteine residues, and disulfide ...
Chemokine (C-X-C motif) ligand 13 (CXCL13), also known as B lymphocyte chemoattractant (BLC) or B cell-attracting chemokine 1 (BCA-1), is a protein ligand that in humans is encoded by the CXCL13 gene. See more CXCL13 is a small chemokine belonging to the CXC chemokine family. As its other names suggest, this chemokine is selectively chemotactic for B cells belonging to both the B-1 and B-2 subsets, and elicits its effects by … See more • Human CXCL13 genome location and CXCL13 gene details page in the UCSC Genome Browser. • Overview of all the structural information available in the PDB for See more WebThe CXCL13 chemokine is chemotactic to cells of the B-1 and B-2 subsets and interacts with the CXCR5 receptor. It acts via BLR1, as is shown by the induced chemotaxis and …
WebBCA-1/ BLC (CXCL13) BRAK (CXCL14) C-10 (CCL6) CTACK (CCL27) CXCL16 CXCL17 CXCL6 ENA-78 (CXCL5) ... The Alpha-Chemokines are referred to also as the 4q chemokine family because the genes encoding members of this family map to human chromosome 4q12-21. The first 2 cysteine residues of this family are separated by 1 …
WebCXCL13/BLC/BCA-1 is a constitutively expressed chemokine that plays an important role in B and T cell homing. It is expressed by salivary gland epithelium, dendritic cells, osteoclasts, and peritoneal macrophages. It … norfolk county council pay bandsWebNaive B cells that recirculate to lymphoid organs express high levels of CXCR5 , which, through interactions with the chemokine BLC, leads to B cell migration into follicular areas and their subsequent maturation. BLC … norfolk county council parkingWebBCA-1/BLC, a CXC chemokine, is expressed in the liver, spleen, lymph nodes, appendix and stomach. It exerts its activities through its only receptor, CXCR5. BCA-1/BLC is a potent chemoattractant for B lymphocytes, and induces weak chemotactic response in T cells and macrophages. It manifests no activity on neutrophils and monocytes. how to remove kids profile from netflixWebApr 11, 2024 · B-Lymphocyte Chemoattractant (BLC), also known as B Cell-Attracting chemokine 1 (BCA-1), or CXCL13, is a member of the CXC subtype of the chemokine superfamily. BLC is critical for secondary lymphoid tissue development and navigation of lymphocytes within the microcompartments of these tissues. norfolk county council phone number norwichWebBCA-1/BLC, a CXC chemokine, is expressed in the liver, spleen, lymph nodes, appendix and stomach. It exerts its activities through its only receptor, CXCR5. BCA-1/BLC is a … norfolk county council prow mapWebAug 26, 2009 · The proximal promoter region of the gene for the CXCL13/BLC chemokine has been studied by electrophoretic mobility shift assay and reporter gene analysis in order to detect new control elements, in particular, NF-κB binding sites. Two new putative control elements have been identified. One of them contains a Rel/NF-κB binding site and … norfolk county council scaffold permitWebJun 18, 2001 · BLC (CXCL13), a CXC chemokine, is the only chemokine so far which is known to specifically chemoattract B cells through the interaction with its receptor … norfolk county council renew library books